Advocate is an easy to use, monthly spot-on treatment that protects your dog from fleas, heartworm, major intestinal worms and ear mites. Protects against heartworm when used monthly. Kills fleas and prevents re-infestation for a month. Treats and controls most major intestinal worms, including hookworm, roundworm and whipworm. Treats and controls ear mites. Safe for use in puppies from 7 weeks of age. The safety of Advocate in pregnant and lactating dogs has not been established.